Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821017 | 0.82 | HDAC4 (0.54) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| SCHEMBL6013603 | 0.79 | NQO1 (0.64) | FFAR1FFAR4NQO1LTA4HNPC1 | |
| SCHEMBL5698011 | 0.76 | LTA4H (0.61) | FFAR1FFAR4NQO1LTA4HNPC1 | |
| SCHEMBL562949 | 0.75 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1HPGDMAPK1KMT2A | |
| SCHEMBL5833074 | 0.75 | FFAR1 (0.58) | FFAR1FFAR4NQO1LTA4HHCRTR1 | |
| SCHEMBL11021395 | 0.75 | NQO1 (0.52) | FFAR1FFAR4NQO1LTA4HHCRTR1 | |
| SCHEMBL7828144 | 0.75 | NQO1 (0.52) | NQO1LTA4HNPC1LMNATSHR | |
| SCHEMBL916574 | 0.74 | ABL1 (0.48) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13211652 | 0.74 | NQO1 (0.56) | FFAR1FFAR4NQO1LTA4HHCRTR1 | |
| SCHEMBL4988323 | 0.73 | NPC1 (0.59) | FFAR1FFAR4HCRTR1HCRTR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |