Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828156 | 0.85 | RORC (0.44) | RORCALDH1A1GAALMNAMAPT | |
| SCHEMBL7828158 | 0.85 | RORC (0.44) | RORCALDH1A1GAALMNAMAPT | |
| SCHEMBL7828163 | 0.73 | RORC (0.44) | RORCALDH1A1GAALMNAMAPT | |
| SCHEMBL4333500 | 0.72 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4333508 | 0.72 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL19436968 | 0.63 | MAPT (0.52) | ALDH1A1GAALMNAMAPTSMN1; SMN2 | |
| SCHEMBL19436969 | 0.63 | MAPT (0.52) | ALDH1A1GAALMNAMAPTSMN1; SMN2 | |
| SCHEMBL5173228 | 0.61 | MAPK13 (0.61) | RORCALDH1A1GAALMNAMAPT | |
| SCHEMBL7593343 | 0.61 | KMT2A (0.57) | RORCALDH1A1GAALMNAMAPT | |
| SCHEMBL13714272 | 0.59 | ALDH1A1 (0.62) | ALDH1A1GAALMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |