Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 11/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27551809 | 0.80 | OPRD1 (0.43) | OPRK1OPRD1OPRM1 | |
| SCHEMBL27551779 | 0.78 | OPRD1 (0.45) | OPRK1OPRD1OPRM1 | |
| SCHEMBL6598934 | 0.75 | OPRK1 (0.77) | OPRK1OPRD1OPRM1 | |
| SCHEMBL27551806 | 0.74 | OPRD1 (0.62) | OPRK1OPRD1OPRM1 | |
| SCHEMBL6601891 | 0.72 | OPRD1 (1.00) | OPRK1OPRD1OPRM1 | |
| SCHEMBL6601046 | 0.72 | OPRD1 (0.84) | OPRK1OPRD1OPRM1 | |
| SCHEMBL6598957 | 0.71 | OPRD1 (1.00) | OPRK1OPRD1OPRM1 | |
| SCHEMBL6601922 | 0.71 | OPRD1 (0.81) | OPRK1OPRD1OPRM1 | |
| SCHEMBL6598465 | 0.70 | OPRD1 (0.70) | OPRK1OPRD1OPRM1 | |
| SCHEMBL7827245 | 0.70 | OPRM1 (0.39) | OPRK1OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140835-A1 | 3,3-BIARYLPIPERIDINE AND 2,2-BIARYLMORPHOLINE DERIVATIVES | Pfizer Products Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039091-A1 | 3,3-BIARYLPIPERIDINE AND 2,2-BIARYLMORPHOLINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2000-07-06 | — | — | WO | disclosed |