Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7828218 | 0.99 | PTGS2 (0.43) | PTGS2CYP3A4TSHRL3MBTL1RAB9A | |
| SCHEMBL27574701 | 0.87 | LMNA (0.39) | PTGS2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL3651806 | 0.86 | PTGS2 (0.63) | PTGS2CYP3A4TSHRL3MBTL1RAB9A | |
| Hydrochloric Acid SCHEMBL4029457 | 0.85 | PTGS2 (0.61) | PTGS2CYP3A4TSHRL3MBTL1RAB9A | |
| Nitric Acid SCHEMBL4027674 | 0.84 | PTGS2 (0.60) | PTGS2CYP3A4TSHRL3MBTL1RAB9A | |
| SCHEMBL7851267 | 0.79 | PTGS2 (0.43) | PTGS2TSHRKDM4EGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7845555 | 0.78 | PTGS2 (0.42) | PTGS2TSHRKDM4EGAAALDH1A1 | |
| SCHEMBL10595586 | 0.78 | LMNA (0.54) | PTGS2ALDH1A1LMNAKMT2A | |
| Nitric Acid SCHEMBL28748383 | 0.77 | PTGS2 (0.42) | PTGS2TSHRKDM4EGAAALDH1A1 | |
| SCHEMBL3033478 | 0.74 | PTGS2 (0.57) | PTGS2CYP3A4TSHRRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154999-A1 | NITROXYDERIVATIVES HAVING ANTIINFLAMMATORY, ANALGESIC AND ANTITHROMBOTIC ACTIVITY | NICOX S.A. (FR) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000051988-A1 | NITROXYDERIVATIVES HAVING ANTIINFLAMMATORY, ANALGESIC AND ANTITHROMBOTIC ACTIVITY | NICOX S.A. (FR) | 2000-09-08 | — | — | WO | disclosed |