Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816440 | 0.93 | UCHL1 (0.40) | ALDH1A1SMN1; SMN2MITFCYP19A1UCHL1 | |
| SCHEMBL7824951 | 0.90 | PTGER4 (0.42) | ALDH1A1MAPTPOLBRXFP1ALOX15 | |
| SCHEMBL7816184 | 0.89 | CYP19A1 (0.44) | ALDH1A1SMN1; SMN2MITFCYP19A1UCHL1 | |
| SCHEMBL7823358 | 0.86 | PTGER4 (0.42) | ALDH1A1MAPTPOLBRXFP1ALOX15 | |
| SCHEMBL7831313 | 0.86 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2MITFCYP19A1UCHL1 | |
| SCHEMBL7831187 | 0.86 | CYP19A1 (0.47) | ALDH1A1SMN1; SMN2MITFCYP19A1UCHL1 | |
| SCHEMBL7831799 | 0.86 | POLB (0.40) | ALDH1A1SMN1; SMN2MITFCYP19A1UCHL1 | |
| SCHEMBL5511589 | 0.85 | MAPT (0.44) | ALDH1A1SMN1; SMN2MITFCYP19A1UCHL1 | |
| SCHEMBL7823456 | 0.85 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2MITFCYP19A1UCHL1 | |
| SCHEMBL8071430 | 0.85 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MITFMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |