Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067007 | 0.94 | KMT2A (0.45) | ALDH1A1KMT2AHPGDAKR1C3MEN1 | |
| SCHEMBL8071906 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KMT2AHPGDAKR1C3MEN1 | |
| SCHEMBL7823983 | 0.90 | LMNA (0.45) | ALDH1A1KMT2AHPGDAKR1C3MEN1 | |
| SCHEMBL7816184 | 0.88 | CYP19A1 (0.44) | ALDH1A1KMT2AHPGDMEN1HSD17B10 | |
| SCHEMBL7831313 | 0.86 | SMN1; SMN2 (0.45) | ALDH1A1KMT2AHPGDMEN1HSD17B10 | |
| SCHEMBL7831187 | 0.86 | CYP19A1 (0.47) | ALDH1A1HPGDAKR1C3MAPTPOLB | |
| SCHEMBL7831799 | 0.85 | POLB (0.40) | ALDH1A1KMT2AHPGDMEN1HSD17B10 | |
| SCHEMBL5511589 | 0.85 | MAPT (0.44) | ALDH1A1HPGDHSD17B10MAPTPOLB | |
| SCHEMBL7828234 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KMT2AHPGDMEN1HSD17B10 | |
| SCHEMBL7816556 | 0.84 | LMNA (0.44) | ALDH1A1KMT2AHPGDAKR1C3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |