Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 12/20 | 1.00 |
| ▸ | PDE1A | P54750 | 5/20 | 1.00 |
| ▸ | PDE1B | Q01064 | 5/20 | 1.00 |
| ▸ | PDE1C | Q14123 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | PDE2A | O00408 | 4/20 | 0.66 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402437 | 0.99 | PDE5A (0.97) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL1111560 | 0.90 | PDE5A (0.81) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL2917588 | 0.85 | PDE5A (0.74) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL4622439 | 0.84 | PDE5A (0.73) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL7089133 | 0.82 | PDE5A (0.70) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL10960178 | 0.82 | PDE5A (0.70) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL14889319 | 0.82 | PDE5A (1.00) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL4622802 | 0.81 | PDE5A (0.68) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL897036 | 0.80 | PDE1A (1.00) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL9927457 | 0.80 | PDE1A (0.66) | PDE5APDE1APDE1BPDE1CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-222882781-U | M.2 signal integrity test fixture supporting PCIE5.0 | 深圳市同泰怡信息技术有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-118819027-A | Front-end readout electronics system of scintillator detector based on multichannel waveform digitizing chip | 中国科学院紫金山天文台 | 2024-10-22 | — | — | CN | claimed |
| CN-117743053-A | High-speed signal processing method, device, equipment and system | 西安易朴通讯技术有限公司 | 2024-03-22 | — | — | CN | claimed |
| US-20220378782-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-12-01 | — | — | US | claimed |
| US-20190083455-A1 | METHODS AND COMPOSITIONS FOR THE MODULATION OF BETA-ENDORPHIN LEVELS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-03-21 | — | — | US | claimed |
| US-20170105964-A1 | METHODS AND COMPOSITIONS FOR THE MODULATION OF BETA-ENDORPHIN LEVELS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-04-20 | — | — | US | claimed |
| US-20160045617-A1 | TREATMENT OF PROXIMAL SPINAL MUSCULAR ATROPHY | LEE JUSTIN C (US) | 2016-02-18 | — | — | US | claimed |
| WO-2015195894-A1 | METHODS AND COMPOSITIONS FOR THE MODULATION OF BETA-ENDORPHIN LEVELS | THE GENERAL HOSPITAL CORPORATION (US) | 2015-12-23 | — | — | WO | claimed |
| WO-2014169087-A2 | TREATMENT OF PROXIMAL SPINAL MUSCULAR ATROPHY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-10-16 | — | — | WO | claimed |
| US-20080193385-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROPATHY | MAIBACH TODD | 2008-08-14 | — | — | US | claimed |
| US-20050009847-A1 | Compounds and methods for increasing neurogenesis | NEURONOVA AB (COMPANY REGISTRATION NO. 556703-0118) (SE) | 2005-01-13 | — | — | US | claimed |
| US-6812239-B2 | DETERMINING IF COMPOUND INHIBITS PHOSPHODIESTERASE 1C (PDE1C) IN PANCREATIC ISLET BETA-CELLS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY | 2004-11-02 | — | — | US | claimed |
| WO-2004045592-A2 | COMPOUNDS AND METHODS FOR INCREASING NEUROGENESIS | NEURONOVA AB (SE) | 2004-06-03 | — | — | WO | claimed |
| US-6586478-B2 | Administering nitrogen oxide mimetic | CELLEGY CANADA (CA) | 2003-07-01 | — | — | US | claimed |
| EP-1305328-A2 | MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES | Lyles, Mark B. (US) | 2003-05-02 | — | — | EP | claimed |
| US-20020103350-A1 | Materials and methods for binding nucleic acids to surfaces | LYLES MARK B (US) | 2002-08-01 | — | — | US | claimed |
| WO-2002008237-A2 | MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES | LYLES MARK B (US) | 2002-01-31 | — | — | WO | claimed |
| EP-0502043-B1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECH (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0502043-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR. | LVMH RECH (FR) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007945-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECHERCHE (FR) | 1991-06-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220378782-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | MECP2, SLC1A2, GRIN2C | PDE5A 3425/4885PDE1A 1674/4885PDE1B 1494/4885 |
| US-20160045617-A1 | TREATMENT OF PROXIMAL SPINAL MUSCULAR ATROPHY | CELF2, SMN1; SMN2, GRM8 | PDE5A 248/4885PDE1A 55/4885PDE1B 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.