Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 5/20 | 0.37 |
| ▸ | GSK3B | P49841 | 5/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783043 | 0.85 | CDK1 (0.52) | DNMT1CDK1GSK3BCCNB2CCNB1 | |
| SCHEMBL782285 | 0.83 | PGR (0.35) | DNMT1CDK1GSK3BCCNB2CCNB1 | |
| SCHEMBL30866249 | 0.83 | PGR (0.35) | DNMT1CDK1GSK3BCCNB2CCNB1 | |
| SCHEMBL783165 | 0.81 | MEN1 (0.32) | TSPOPDK2SRCRXFP1 | |
| SCHEMBL783169 | 0.80 | PRMT5 (0.37) | GSK3BEGFR | |
| SCHEMBL782446 | 0.79 | MDM2 (0.32) | DNMT1CDK1GSK3BCCNB2CCNB1 | |
| SCHEMBL783189 | 0.79 | PDK2 (0.38) | PDK2 | |
| SCHEMBL8819147 | 0.78 | PGR (0.35) | DNMT1CDK1GSK3BCCNB2CCNB1 | |
| SCHEMBL782265 | 0.78 | TSPO (0.36) | TSPOPDK2 | |
| SCHEMBL14880687 | 0.77 | GSK3B (0.30) | CDK1GSK3BCCNB2CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9537105-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-01-03 | — | — | US | disclosed |
| US-20150318478-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-9126970-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-09-08 | — | — | US | disclosed |
| US-20120068170-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150318478-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO2B1, SLCO1B3, SLCO4C1 | DNMT1 496/4885CDK1 2210/4885GSK3B 2430/4885 |
| US-20120068170-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO2B1, SLCO1B3, SLCO4C1 | DNMT1 496/4885CDK1 2210/4885GSK3B 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.