Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.39 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.39 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753156 | 0.76 | BACE1 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9355248 | 0.76 | BACE1 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8434070 | 0.70 | RAB9A (0.67) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9093258 | 0.67 | RAB9A (0.69) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9664553 | 0.67 | RAB9A (0.69) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8336518 | 0.67 | BACE1 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13922829 | 0.66 | RAB9A (0.67) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL17817587 | 0.65 | RAB9A (0.66) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL13668923 | 0.65 | EGFR (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL13922820 | 0.64 | RAB9A (0.64) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |