Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753156 | 1.00 | BACE1 (0.41) | BACE1HSD17B10GABRA5GABRB2ALDH1A1 | |
| SCHEMBL8336518 | 0.88 | BACE1 (0.41) | BACE1HSD17B10GABRA5GABRB2ALDH1A1 | |
| SCHEMBL8871075 | 0.76 | HSD17B10 (0.41) | BACE1HSD17B10GABRA5GABRB2ALDH1A1 | |
| SCHEMBL9483248 | 0.76 | PTPRB (0.39) | HSD17B10GABRA5GABRB2MEN1KMT2A | |
| SCHEMBL7828361 | 0.76 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL27568111 | 0.76 | HSD17B10 (0.38) | BACE1HSD17B10GABRA5GABRB2ALDH1A1 | |
| SCHEMBL1565803 | 0.75 | HSD17B10 (0.46) | BACE1HSD17B10GABRA5GABRB2ALDH1A1 | |
| SCHEMBL27386599 | 0.75 | GABRA5 (0.37) | BACE1HSD17B10GABRA5GABRB2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27656212 | 0.75 | GABRA5 (0.37) | BACE1HSD17B10GABRA5GABRB2ALDH1A1 | |
| SCHEMBL10976928 | 0.74 | CASP2 (0.41) | ALDH1A1SMN1; SMN2MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347777-B1 | Process for preparing cephalosporins and intermediates therefor | BIOCHEMIE SA (ES) | 1994-11-09 | — | — | EP | disclosed |