Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
| ▸ | PKM | P14618 | 1/20 | 0.76 |
| ▸ | CASP3 | P42574 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | PLEC | Q15149 | 1/20 | 0.76 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.76 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.76 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.68 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.68 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828469 | 1.00 | KDM4E (0.76) | KDM4EL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL13980482 | 0.86 | KDM4E (0.83) | KDM4EL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL7767009 | 0.83 | NR4A2 (0.81) | MEN1KMT2ASMN1; SMN2NR4A1NR4A2 | |
| SCHEMBL6830467 | 0.83 | NR4A2 (1.00) | MEN1KMT2APKMSMN1; SMN2NR4A1 | |
| SCHEMBL4059143 | 0.83 | NR4A2 (1.00) | MEN1KMT2APKMSMN1; SMN2NR4A1 | |
| SCHEMBL228477 | 0.83 | NR4A2 (1.00) | MEN1KMT2APKMSMN1; SMN2NR4A1 | |
| SCHEMBL8806871 | 0.82 | KDM4E (0.77) | KDM4EL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8806870 | 0.82 | KDM4E (0.77) | KDM4EL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL525302 | 0.82 | KDM4E (0.77) | KDM4EL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL1032816 | 0.82 | KDM4E (0.77) | KDM4EL3MBTL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |