Trimethylammonium

Trimethylammonium

SCHEMBL782850

C=CC=CC=C(c1ccccc1)c1ccccc1.CN(C)C

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
AKT1 P31749 1/20 0.36
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HSP90AA1 P07900 1/20 0.35
RECQL P46063 1/20 0.35
LMNA P02545 1/20 0.35
SIGMAR1 Q99720 1/20 0.34
EGFR P00533 2/20 0.33
CYP2D6 P10635 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
RAB9A P51151 2/20 0.32
NPC1 O15118 1/20 0.32
HPGD P15428 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133924 0.92 AKT1 (0.41) ALDH1A1AKT1MAPTMEN1KMT2A
SCHEMBL133925 0.92 AKT1 (0.41) ALDH1A1AKT1MAPTMEN1KMT2A
SCHEMBL1931541 0.90 AKT1 (0.40) ALDH1A1AKT1MAPTMEN1KMT2A
SCHEMBL1931543 0.90 AKT1 (0.40) ALDH1A1AKT1MAPTMEN1KMT2A
Propionic Acid SCHEMBL1525114 0.82 CES2 (0.42) ALDH1A1AKT1MAPTRECQLLMNA
Propionic Acid SCHEMBL1525115 0.82 CES2 (0.42) ALDH1A1AKT1MAPTRECQLLMNA
SCHEMBL6415855 0.81 TSHR (0.50) ALDH1A1AKT1MAPTRECQLRAB9A
SCHEMBL11221544 0.81 TDP1 (0.43) ALDH1A1AKT1MAPTRECQLMTNR1A
SCHEMBL11221549 0.81 TDP1 (0.43) ALDH1A1AKT1MAPTRECQLMTNR1A
SCHEMBL57798 0.77 AKT1 (0.46) ALDH1A1AKT1MAPTRECQLMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210106687-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LAUREN SCIENCES LLC 2021-04-15 US disclosed
EP-3532024-B1 COSMETIC USE AND METHOD FOR IMPROVING PHYSIOLOGICAL FUNCTIONS OF THE SKIN BY INCREASING THE EXPRESSION OF UBIAD1 ISP INVESTMENTS LLC (US) 2021-02-24 EP disclosed
US-20190269596-A1 COSMETIC USE AND METHOD FOR IMPROVING PHYSIOLOGICAL FUNCTIONS OF THE SKIN BY INCREASING THE EXPRESSION OF UBIAD1 ISP INVESTMENTS LLC (US) 2019-09-05 US disclosed
EP-3532024-A1 COSMETIC USE AND METHOD FOR IMPROVING PHYSIOLOGICAL FUNCTIONS OF THE SKIN BY INCREASING THE EXPRESSION OF UBIAD1 ISP Investments LLC (US) 2019-09-04 EP disclosed
US-20190076533-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LAUREN SCIENCES LLC (US) 2019-03-14 US disclosed
EP-2252304-B1 PLATINUM AGGREGATES AND PROCESS FOR PRODUCING THE SAME TRANSAVE INC (US) 2018-07-18 EP disclosed
WO-2018078079-A1 COSMETIC USE AND METHOD FOR IMPROVING PHYSIOLOGICAL FUNCTIONS OF THE SKIN BY INCREASING THE EXPRESSION OF UBIAD1 ISP INVESTMENTS LLC (US) 2018-05-03 WO disclosed
US-20160263030-A1 PLATINUM AGGREGATES AND PROCESS FOR PRODUCING THE SAME INSMED INC (US) 2016-09-15 US disclosed
US-20160166608-A1 METHODS OF TREATING CANCER WITH HIGH POTENCY LIPID-BASED PLATINUM COMPOUND FORMULATIONS ADMINISTERED INTRAPERITONEALLY INSMED INC (US) 2016-06-16 US disclosed
US-9186322-B2 Platinum aggregates and process for producing the same INSMED INCORPORATED (US) 2015-11-17 US disclosed
US-20120070490-A1 ANTI-TRYPANOSOMAL PEPTIDES AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2012-03-22 US disclosed
EP-2252304-A2 PLATINUM AGGREGATES AND PROCESS FOR PRODUCING THE SAME Transave, Inc. (US) 2010-11-24 EP disclosed
WO-2009100330-A2 PLATINUM AGGREGATES AND PROCESS FOR PRODUCING THE SAME TRANSAVE, INC. (US) 2009-08-13 WO disclosed
US-20090130193-A1 Methods of Treating Cancer with High Potency Lipid-Based Platinum Compound Formulations Administered Intraperitoneally TRANSAVE, INC. (US) 2009-05-21 US disclosed
US-20090130194-A1 Methods of Treating Cancer with High Potency Lipid-Based Platinum Compound Formulations Administered Intravenously TRANSAVE, INC. (US) 2009-05-21 US disclosed
US-20080187578-A1 Complex of lipid and platimun compound TRANSAVE, INC. (US) 2008-08-07 US disclosed
EP-1545459-A4 PLATINUM AGGREGATES AND PROCESS FOR PRODUCING THE SAME TRANSAVE INC (US) 2007-08-22 EP disclosed
EP-1545459-A2 PLATINUM AGGREGATES AND PROCESS FOR PRODUCING THE SAME Transave, Inc. (US) 2005-06-29 EP disclosed
WO-2004054499-A2 PLATINUM AGGREGATES AND PROCESS FOR PRODUCING THE SAME TRANSAVE, INC. (US) 2004-07-01 WO disclosed
US-20040101553-A1 Platinum aggregates and process for producing the same TRANSAVE, INC. 2004-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210106687-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LGALS1, BOLA2; BOLA2B, LGALS2 ALDH1A1 344/4885AKT1 4089/4885MAPT 856/4885
US-20090130193-A1 Methods of Treating Cancer with High Potency Lipid-Based Platinum Compound Formulations Administered Intraperitoneally SGMS2, SGMS1, LPCAT3 ALDH1A1 1280/4885AKT1 1560/4885MAPT 4613/4885
US-20160166608-A1 METHODS OF TREATING CANCER WITH HIGH POTENCY LIPID-BASED PLATINUM COMPOUND FORMULATIONS ADMINISTERED INTRAPERITONEALLY SGMS2, SGMS1, LPCAT3 ALDH1A1 1280/4885AKT1 1560/4885MAPT 4613/4885
US-20090130194-A1 Methods of Treating Cancer with High Potency Lipid-Based Platinum Compound Formulations Administered Intravenously SGMS1, SGMS2, PHOSPHO1 ALDH1A1 2059/4885AKT1 2187/4885MAPT 4172/4885
US-20190076533-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LGALS1, BOLA2; BOLA2B, LGALS2 ALDH1A1 408/4885AKT1 4321/4885MAPT 1095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.