Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754982 | 0.86 | KDM5A (0.52) | KDM5AKDM5BMAP3K5LMNAMAPT | |
| SCHEMBL7754979 | 0.82 | KDM5A (0.53) | KDM5AKDM5BMAP3K5LMNAMAPT | |
| SCHEMBL321963 | 0.81 | KDM5A (0.54) | KDM5AKDM5BMAP3K5LMNAMAPT | |
| SCHEMBL1033018 | 0.80 | KDM5A (0.53) | KDM5AKDM5BMAP3K5LMNAMAPT | |
| SCHEMBL7861387 | 0.77 | KDM5A (0.50) | KDM5AKDM5BMAP3K5LMNAMAPT | |
| SCHEMBL7828560 | 0.75 | GPBAR1 (0.40) | LMNAMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL322275 | 0.74 | USP2 (0.44) | KDM5AKDM5BMEN1KMT2AALDH1A1 | |
| SCHEMBL14829878 | 0.74 | GAA (0.51) | KDM5AKDM5BLMNAMAPTMEN1 | |
| SCHEMBL321856 | 0.72 | KDM5A (0.44) | KDM5AKDM5BMAP3K5LMNAMAPT | |
| SCHEMBL16029767 | 0.72 | MAP3K5 (0.60) | KDM5AKDM5BMAP3K5MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095021-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000003991-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2000-01-27 | — | — | WO | disclosed |