Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911580 | 0.87 | PKM (0.58) | HSD17B10PKMTPMTKDM4ELCK | |
| SCHEMBL27467767 | 0.83 | TSHR (0.46) | TSHRHSD17B10PKMTPMTKDM4E | |
| SCHEMBL23489254 | 0.80 | KDM4E (0.56) | TSHRHSD17B10PKMTPMTKDM4E | |
| SCHEMBL16168327 | 0.79 | HMGCR (0.54) | HSD17B10PKMTPMTKDM4ELCK | |
| SCHEMBL4809375 | 0.79 | PKM (0.48) | HSD17B10PKMTPMTKDM4ELCK | |
| SCHEMBL6394441 | 0.77 | PKM (0.55) | HSD17B10PKMTPMTKDM4ELCK | |
| SCHEMBL18309198 | 0.76 | TSHR (0.66) | TSHRHSD17B10KDM4ELCKFYN | |
| SCHEMBL8555013 | 0.76 | KDM4E (0.49) | TSHRHSD17B10PKMKDM4ENEK2 | |
| SCHEMBL16181544 | 0.76 | KDM4E (0.63) | HSD17B10PKMTPMTKDM4ELCK | |
| SCHEMBL4359214 | 0.75 | HSD17B10 (0.50) | HSD17B10PKMTPMTKDM4ELCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |