Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827167 | 0.93 | DCTPP1 (0.45) | DCTPP1L3MBTL1TDP1AKR1C3ALOX15 | |
| SCHEMBL7827410 | 0.90 | CYP19A1 (0.43) | DCTPP1L3MBTL1AKR1C3ALOX15POLB | |
| SCHEMBL7828209 | 0.86 | DCTPP1 (0.43) | DCTPP1L3MBTL1AKR1C3ALOX15POLB | |
| SCHEMBL7830851 | 0.86 | HPGD (0.50) | DCTPP1L3MBTL1AKR1C3ALOX15PTGER4 | |
| SCHEMBL7831794 | 0.85 | HPGD (0.52) | DCTPP1L3MBTL1AKR1C3ALOX15AKR1C2 | |
| SCHEMBL7829292 | 0.85 | ALOX15 (0.42) | DCTPP1L3MBTL1AKR1C3ALOX15PTGER4 | |
| SCHEMBL7823265 | 0.85 | ALOX15 (0.48) | L3MBTL1AKR1C3ALOX15AKR1C2POLB | |
| SCHEMBL7816277 | 0.83 | POLB (0.43) | DCTPP1L3MBTL1TDP1AKR1C3ALOX15 | |
| SCHEMBL7825463 | 0.82 | ALOX15 (0.42) | DCTPP1L3MBTL1TDP1AKR1C3ALOX15 | |
| SCHEMBL7830535 | 0.81 | ALOX15 (0.41) | DCTPP1L3MBTL1TDP1AKR1C3ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |