Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828758 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL8091366 | 0.83 | NOTUM (0.43) | SMN1; SMN2L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL7403188 | 0.81 | KDM4E (0.47) | SMN1; SMN2L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL19985029 | 0.78 | ALDH1A1 (0.45) | SMN1; SMN2L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL31686158 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL3703857 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL10929155 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL7041505 | 0.76 | SRD5A2 (0.50) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL10930335 | 0.76 | NOTUM (0.44) | SMN1; SMN2ALDH1A1MTNR1AMTNR1BNOTUM | |
| SCHEMBL24821262 | 0.74 | ALDH1A1 (0.49) | SMN1; SMN2L3MBTL1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820450-B1 | N-substituted azaheterocyclic carboxylic acids and alkylesters thereof | NOVO NORDISK AS (DK) | 2001-09-12 | — | — | EP | disclosed |