Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19985029 | 0.92 | ALDH1A1 (0.45) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL3703857 | 0.85 | SMN1; SMN2 (0.42) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL31686158 | 0.85 | SMN1; SMN2 (0.42) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL24821194 | 0.82 | KDM4C (0.45) | BRD4PPARG | |
| SCHEMBL8515359 | 0.82 | MPO (0.51) | ALDH1A1L3MBTL1HPGDSMN1; SMN2BRD4 | |
| SCHEMBL27366916 | 0.82 | MAPT (0.42) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL31618140 | 0.82 | MPO (0.42) | BRD4PPARGMPO | |
| SCHEMBL10530875 | 0.82 | MPO (0.42) | KDM4EALDH1A1L3MBTL1HPGDTDP1 | |
| SCHEMBL7401882 | 0.82 | SIGMAR1 (0.45) | KDM4EALDH1A1HPGDNOTUM | |
| SCHEMBL9482430 | 0.81 | MPO (0.64) | KDM4EL3MBTL1TDP1SMN1; SMN2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512843-B1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-20 | — | — | EP | disclosed |
| US-11136292-B2 | Plant growth regulator compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-05 | — | — | US | disclosed |
| US-20190330148-A1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-31 | — | — | US | disclosed |
| WO-2018050477-A1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |
| WO-2017208253-A2 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF IVACAFTOR | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-12-07 | — | — | WO | disclosed |
| EP-2730918-B1 | MATRIX FOR MALDI MASS SPECTROMETRY AND MALDI MASS SPECTROMETRY METHOD | UNIV KYUSHU NAT UNIV CORP (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-20140151548-A1 | MATRIX FOR MALDI MASS SPECTROMETRY AND MALDIMASS SPECTROMETRY METHOD | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2730918-A1 | MATRIX FOR MALDI MASS SPECTROMETRY | Kyushu University National University Corporation (JP) | 2014-05-14 | — | — | EP | disclosed |
| CN-101429125-A | Synthesis of (7-methoxy-3, 4-dihydrogen-1-naphthyl) ethyl acetate | SHANGHAI INST PHARM INDUSTRY (CN) | 2009-05-13 | — | — | CN | disclosed |
| US-6133446-A | Heterocyclic compounds for the treatment of CNS and cardiovascular disorders | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| CN-1046507-C | Heterocyclic compounds for the treatment of central nervous system and cardiovascular diseases | UPJOHN CO (US) | 1999-11-17 | — | — | CN | disclosed |
| US-5877317-A | Heterocyclic compounds for the treatment of CNS and cardiovascular disorders | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| CN-1139431-A | Heterocyclic compounds for the treatment of central nervous system and cardiovascular diseases | PHARMACIA & UPJOHN CO LLC (US) | 1997-01-01 | — | — | CN | disclosed |
| EP-0737189-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CNS AND CARDIOVASCULAR DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 1996-10-16 | — | — | EP | disclosed |
| EP-0490772-B1 | 1,4-Disubstituted piperazines, their process of preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-07-26 | — | — | EP | disclosed |
| WO-1995018118-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CNS AND CARDIOVASCULAR DISORDERS | THE UPJOHN COMPANY (US) | 1995-07-06 | — | — | WO | disclosed |
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11136292-B2 | Plant growth regulator compounds | FGF1, MST1, CDC20 | KDM4E 3400/4885ALDH1A1 3543/4885L3MBTL1 3472/4885 |
| US-20190330148-A1 | PLANT GROWTH REGULATOR COMPOUNDS | FGF1, MST1, CDC20 | KDM4E 3400/4885ALDH1A1 3543/4885L3MBTL1 3472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.