Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829572 | 0.85 | GAA (0.39) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4422464 | 0.84 | ALDH1A1 (0.37) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL607586 | 0.76 | L3MBTL1 (0.39) | L3MBTL1PKMMEN1KMT2AGFER | |
| SCHEMBL6930683 | 0.73 | PDE4A (0.46) | L3MBTL1PKMMEN1KMT2AJAK2 | |
| SCHEMBL11519279 | 0.71 | MEN1 (0.46) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7477762 | 0.70 | GSK3B (0.41) | MEN1KMT2ACYP1A2RAB9ANPC1 | |
| SCHEMBL7835439 | 0.69 | ALDH1A1 (0.41) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8618927 | 0.65 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1IDO1 | |
| SCHEMBL8543734 | 0.63 | HTR2A (0.46) | L3MBTL1PKMMEN1KMT2AJAK2 | |
| SCHEMBL20894117 | 0.61 | GFER (0.34) | PKMKMT2AGFERCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089977-A1 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | Elan Pharmaceuticals, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067219-A1 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1999-12-29 | — | — | WO | disclosed |