Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.49 |
| ▸ | F13A1 | P00488 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PTGIS | Q16647 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829764 | 1.00 | MAPT (0.50) | MAPTRXFP1TBXAS1F13A1MEN1 | |
| SCHEMBL7832915 | 1.00 | MAPT (0.50) | MAPTRXFP1TBXAS1F13A1MEN1 | |
| SCHEMBL2849208 | 0.88 | CCNC (0.48) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL30873960 | 0.88 | CCNC (0.48) | MEN1KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7832111 | 0.86 | HDAC1 (0.54) | TBXAS1 | |
| SCHEMBL2837957 | 0.82 | CASP1 (0.44) | — | |
| SCHEMBL6842066 | 0.81 | TDP1 (0.59) | MAPTRXFP1F13A1MEN1KMT2A | |
| SCHEMBL710750 | 0.81 | TDP1 (0.59) | MAPTRXFP1F13A1MEN1KMT2A | |
| SCHEMBL3732554 | 0.81 | TDP1 (0.59) | MAPTRXFP1F13A1MEN1KMT2A | |
| SCHEMBL1616841 | 0.81 | TDP1 (0.59) | MAPTRXFP1F13A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5804601-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, BACTERIAL OR VIRAL MENINGITIS, DOWN'S SYNDROME AND PARKINSON'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |