Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30105934 | 0.87 | PKM (0.69) | PKMTDP1L3MBTL1KDM4EPOLB | |
| SCHEMBL621983 | 0.87 | PKM (0.69) | PKMTDP1L3MBTL1KDM4EPOLB | |
| SCHEMBL27748861 | 0.84 | TDP1 (0.62) | PKMTDP1L3MBTL1KDM4EPOLB | |
| SCHEMBL29033627 | 0.81 | PKM (0.75) | PKMTDP1L3MBTL1KDM4EPOLB | |
| SCHEMBL30498928 | 0.81 | PKM (0.75) | PKMTDP1L3MBTL1KDM4EPOLB | |
| SCHEMBL1977244 | 0.81 | HPGD (0.49) | PKMTDP1L3MBTL1KDM4EPOLB | |
| SCHEMBL28114768 | 0.80 | ALDH1A1 (0.53) | PKMTDP1L3MBTL1KDM4EPOLB | |
| SCHEMBL27448977 | 0.80 | MAPT (0.55) | PKMTDP1L3MBTL1KDM4EPOLB | |
| SCHEMBL6150576 | 0.79 | LMNA (0.46) | PKMTDP1L3MBTL1KDM4EPOLB | |
| SCHEMBL5962811 | 0.79 | PKM (0.58) | PKMTDP1L3MBTL1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109812-A2 | PYRROLOBENZODIAZEPINES | Spirogen Limited (GB) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012508-A2 | PYRROLBENZODIAZEPINES | SPIROGEN LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |