Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829270 | 1.00 | CASP3 (0.46) | CASP3SENP8SENP7SENP6NOS3 | |
| SCHEMBL5737906 | 0.92 | MAPT (0.44) | CASP3SENP8SENP7SENP6NOS3 | |
| SCHEMBL5737905 | 0.92 | MAPT (0.44) | CASP3SENP8SENP7SENP6NOS3 | |
| SCHEMBL5737830 | 0.85 | MAPT (0.39) | NOS3ALDH1A1LMNAHTTTAAR1 | |
| SCHEMBL5735950 | 0.85 | NPC1 (0.39) | NOS3ALDH1A1LMNAHTTTAAR1 | |
| SCHEMBL8773925 | 0.85 | TAAR1 (0.40) | CASP3SENP8SENP7SENP6NOS3 | |
| SCHEMBL8818079 | 0.84 | NOS3 (0.45) | NOS3ALDH1A1LMNAHTTNOS2 | |
| SCHEMBL5734338 | 0.82 | MAPT (0.36) | NOS3ALDH1A1LMNAHTTNOS2 | |
| SCHEMBL5734335 | 0.82 | MAPT (0.36) | NOS3ALDH1A1LMNAHTTNOS2 | |
| SCHEMBL23178803 | 0.80 | MAPT (0.41) | NOS3ALDH1A1LMNAHTTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712394-B1 | ARTHROPODICIDAL OXAZOLINES AND THIAZOLINES | DU PONT (US) | 2001-11-28 | — | — | EP | disclosed |