SCHEMBL7829376

SCHEMBL7829376

C=CCc1ccc2[nH]n[c]c2c1CC=C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.30
GABRB2 P47870 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1176402 0.79 GABRA1 (0.41) GABRA1GABRB2
SCHEMBL1918099 0.72 GABRA1 (0.43) GABRA1GABRB2
SCHEMBL28217759 0.71 CCNB2 (0.30)
SCHEMBL10904076 0.66 GABRA1 (0.39) GABRA1GABRB2
SCHEMBL45432 0.66 GABRA1 (0.53) GABRA1GABRB2
SCHEMBL9297409 0.64 GABRA1 (0.52) GABRA1GABRB2
SCHEMBL3666835 0.64 GABRA1 (0.40) GABRA1GABRB2
SCHEMBL18136 0.64 GABRA1 (0.56) GABRA1GABRB2
SCHEMBL1005361 0.63 GABRA1 (0.55) GABRA1GABRB2
SCHEMBL1119848 0.63 GABRA1 (0.36) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609905-B1 3-(Nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones UPJOHN CO (US) 2001-06-06 EP disclosed
EP-0609905-A1 3-(Nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones THE UPJOHN COMPANY (US) 1994-08-10 EP disclosed
US-5225565-A Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones THE UPJOHN COMPANY (US) 1993-07-06 US disclosed
US-5182403-A Bactericides, treatment of AIDS THE UPJOHN COMPANY (US) 1993-01-26 US disclosed
US-5164510-A Bactericides THE UPJOHN COMPANY (US) 1992-11-17 US disclosed
EP-0434714-A1 IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES THE UPJOHN COMPANY (US) 1991-07-03 EP disclosed
WO-1990002744-A1 IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES THE UPJOHN COMPANY (US) 1990-03-22 WO disclosed
EP-0359418-A1 5'-Indolinyl-5beta-amidomethyloxazolidin-2-ones, 3-(fused-ring substituted)phenyl-5beta-amidomethyloxazolidin-2-ones and 3-(nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones THE UPJOHN COMPANY (US) 1990-03-21 EP disclosed