Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103158 | 0.70 | MAOB (0.63) | PTPRCPTPN1MAOBMAOANPC1 | |
| SCHEMBL30036439 | 0.70 | MAOB (0.63) | PTPRCPTPN1MAOBMAOANPC1 | |
| SCHEMBL4267264 | 0.70 | PRKDC (0.40) | PTPRCPTPN1MAOBMAOAKMT2A | |
| SCHEMBL4269309 | 0.68 | PTPRC (0.40) | PTPRCPTPN1MAOBMAOAKMT2A | |
| SCHEMBL2150499 | 0.66 | MAOB (0.59) | PTPRCPTPN1MAOBMAOANPC1 | |
| SCHEMBL30417366 | 0.65 | RAB9A (0.68) | PTPRCPTPN1MAOBMAOAKMT2A | |
| SCHEMBL7125605 | 0.65 | MAOB (0.68) | PTPRCPTPN1MAOBMAOAKMT2A | |
| SCHEMBL2149640 | 0.65 | MAOB (0.57) | PTPRCPTPN1MAOBMAOANPC1 | |
| SCHEMBL7125503 | 0.64 | MAOB (0.52) | PTPRCPTPN1MAOBMAOAKMT2A | |
| SCHEMBL731363 | 0.63 | MAOB (0.71) | PTPRCPTPN1MAOBMAOAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109799-A1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000061571-A1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-10-19 | — | — | WO | disclosed |