Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27003086 | 1.00 | THRB (0.39) | THRBTDP1MAPTALDH1A1POLB | |
| Oxalic Acid SCHEMBL27003085 | 0.88 | THRB (0.40) | THRBTDP1MAPTALDH1A1ALOX12 | |
| Oxalic Acid SCHEMBL27135274 | 0.88 | THRB (0.40) | THRBTDP1MAPTALDH1A1ALOX12 | |
| Pivalate SCHEMBL7826838 | 0.85 | ALDH1A1 (0.40) | THRBTDP1MAPTALDH1A1L3MBTL1 | |
| Lactic Acid SCHEMBL7826153 | 0.84 | TP53 (0.42) | THRBTDP1MAPTALDH1A1POLB | |
| SCHEMBL27453889 | 0.84 | POLB (0.39) | THRBTDP1MAPTALDH1A1POLB | |
| Phthalic Acid SCHEMBL18663463 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1POLBALOX12L3MBTL1 | |
| Benzoic Acid SCHEMBL7827449 | 0.83 | TSHR (0.58) | ALDH1A1CES2CES1NAPRTGAA | |
| Phthalic Acid SCHEMBL27539445 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1POLBALOX12L3MBTL1 | |
| Succinic Acid SCHEMBL7829045 | 0.83 | APEX1 (0.48) | MAPTALDH1A1POLBALOX12L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529520-A | Fluoroelastomer compositions containing curative | 杜邦特种产品美国有限公司 | 2024-02-06 | — | — | CN | disclosed |
| EP-4305096-A1 | FLUOROELASTOMERS COMPOSITION COMPRISING CURING AGENTS | Dupont Specialty Products USA, LLC (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022192006-A1 | FLUOROELASTOMERS COMPOSITION COMPRISING CURING AGENTS | DUPONT POLYMERS, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| EP-0679640-B1 | Carboxylate and heat-sensitive recording material using same | MITSUI CHEMICALS INC (JP) | 2001-08-08 | — | — | EP | disclosed |
| CN-1114431-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS (JP) | 1996-01-03 | — | — | CN | disclosed |