Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.57 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429668 | 0.86 | PPARG (0.53) | PPARGPPARA | |
| SCHEMBL4744468 | 0.83 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL8716289 | 0.81 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL8716282 | 0.80 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL7826285 | 0.80 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL6802249 | 0.78 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL7825286 | 0.77 | PPARG (0.74) | PPARGPPARA | |
| SCHEMBL6806357 | 0.77 | ATP4A (0.57) | PPARGPPARA | |
| SCHEMBL7826101 | 0.76 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL15474984 | 0.76 | MAOB (0.62) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648212-B1 | BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES AS PHARMACEUTICAL | SMITHKLINE BEECHAM PLC (GB) | 2001-10-24 | — | — | EP | disclosed |
| EP-1000938-A1 | Heterocyclic compounds as pharmaceuticals | SMITHKLINE BEECHAM PLC (GB) | 2000-05-17 | — | — | EP | disclosed |
| US-6048883-A | HYPOGLYCEMIC AGENT | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-04-11 | — | — | US | disclosed |
| EP-0648212-A1 | HETEROCYCLIC COMPOUNDS AS PHARMACEUTICAL | SMITHKLINE BEECHAM PLC (GB) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001420-A1 | HETEROCYCLIC COMPOUNDS AS PHARMACEUTICAL | SMITHKLINE BEECHAM PLC (GB) | 1994-01-20 | — | — | WO | disclosed |