Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 6/20 | 0.45 |
| ▸ | CALCRL | Q16602 | 14/20 | 0.43 |
| ▸ | RAMP1 | O60894 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957916 | 0.87 | CALCA (0.45) | CALCACALCRLRAMP1CYP3A4 | |
| SCHEMBL7831008 | 0.86 | CALCA (0.44) | CALCACALCRLRAMP1CYP3A4 | |
| SCHEMBL4300402 | 0.83 | CALCRL (0.54) | CALCACALCRLRAMP1CYP3A4 | |
| SCHEMBL3964575 | 0.83 | CALCRL (0.54) | CALCACALCRLRAMP1CYP3A4 | |
| SCHEMBL3960532 | 0.80 | CALCRL (0.64) | CALCACALCRLRAMP1CYP3A4 | |
| SCHEMBL3957978 | 0.79 | CALCRL (0.66) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3960031 | 0.77 | CALCRL (0.45) | CALCACALCRLRAMP1CYP3A4 | |
| SCHEMBL3965267 | 0.77 | CALCRL (0.58) | CALCACALCRLRAMP1CYP3A4 | |
| SCHEMBL4304733 | 0.77 | CALCRL (0.58) | CALCACALCRLRAMP1CYP3A4 | |
| SCHEMBL3960056 | 0.77 | CALCRL (0.62) | CALCACALCRLRAMP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010036946-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | RUDOLF KLAUS (DE) | 2001-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010036946-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, SRMS, OPRM1 | CALCA 463/4885CALCRL 276/4885RAMP1 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.