SCHEMBL7831463

SCHEMBL7831463

COc1cccc2c1C(OC)(OC)NC2=N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
GAA P10253 3/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
CA12 O43570 1/20 0.35
CA4 P22748 1/20 0.35
CA14 Q9ULX7 1/20 0.35
TOP1 P11387 1/20 0.35
ALDH1A1 P00352 3/20 0.34
ADRA2B P18089 1/20 0.34
PTGS1 P23219 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
APP P05067 1/20 0.34
HSD17B10 Q99714 2/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7829943 0.85 PDK2 (0.37) ALDH1A1TDP1KDM4EMAPTHPGD
SCHEMBL7816569 0.84 GAA (0.33) CA1CA2CA7CA9GAA
SCHEMBL7828729 0.83 ALDH1A1 (0.36) GAAALDH1A1LMNAMAPK1KMT2A
SCHEMBL7816249 0.79 NSD2 (0.33) KMT2A
SCHEMBL7827943 0.78 PDE5A (0.39) ALDH1A1MAPTLMNATP53CYP3A4
SCHEMBL7815267 0.77 CA2 (0.33) CA2
SCHEMBL7828597 0.76 IGF1R (0.30)
SCHEMBL7825538 0.76 PDK2 (0.39) CA1CA2CA7CA9CA12
SCHEMBL3129229 0.74 ALDH1A1 (0.34) ALDH1A1TDP1HSD17B10KDM4EMAPT
SCHEMBL7827740 0.73 TDP1 (0.40) CA1CA2CA7CA9GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed