Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820856 | 0.89 | SLC10A2 (0.49) | LMNASMN1; SMN2THRBKMT2AMEN1 | |
| SCHEMBL7836104 | 0.88 | FABP3 (0.44) | FABP3FABP4FABP5LMNASMN1; SMN2 | |
| SCHEMBL8633281 | 0.82 | ALDH1A1 (0.44) | FABP3FABP4FABP5LMNASMN1; SMN2 | |
| SCHEMBL14917022 | 0.81 | PDE5A (0.48) | FABP3FABP4FABP5LMNASMN1; SMN2 | |
| SCHEMBL8121664 | 0.81 | FABP3 (0.53) | FABP3FABP4FABP5LMNASMN1; SMN2 | |
| SCHEMBL8495848 | 0.78 | ALDH1A1 (0.47) | FABP3FABP4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7821085 | 0.78 | MAPT (0.44) | FABP3FABP4FABP5LMNASMN1; SMN2 | |
| SCHEMBL7829696 | 0.77 | SLC10A2 (0.49) | SMN1; SMN2THRBKMT2AMEN1NPSR1 | |
| SCHEMBL8139763 | 0.76 | KDM4E (0.42) | FABP3FABP4FABP5SMN1; SMN2KMT2A | |
| SCHEMBL7831730 | 0.76 | FABP3 (0.44) | FABP3FABP4FABP5LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |