Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831617 | 0.90 | SLC10A2 (0.47) | MAPTKMT2AHSD17B10RAB9AKDM4E | |
| SCHEMBL7836104 | 0.80 | FABP3 (0.44) | MAPTKMT2ARAB9AKDM4ELMNA | |
| SCHEMBL14917022 | 0.80 | PDE5A (0.48) | MAPTKMT2AHSD17B10KDM4ELMNA | |
| SCHEMBL8121664 | 0.79 | FABP3 (0.53) | MAPTKMT2AHSD17B10KDM4ELMNA | |
| SCHEMBL7833827 | 0.79 | ALDH1A1 (0.46) | MAPTKMT2AHSD17B10RAB9AKDM4E | |
| SCHEMBL8633281 | 0.78 | ALDH1A1 (0.44) | MAPTKMT2AHSD17B10KDM4ELMNA | |
| SCHEMBL7831737 | 0.78 | FABP3 (0.44) | KMT2AKDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL7832560 | 0.78 | TDP1 (0.40) | MAPTKMT2AHSD17B10KDM4ELMNA | |
| SCHEMBL7822008 | 0.78 | RECQL (0.47) | MAPTKMT2ARAB9AKDM4ELMNA | |
| SCHEMBL7834035 | 0.78 | ALDH1A1 (0.44) | MAPTKMT2AHSD17B10RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |