SCHEMBL7832016

SCHEMBL7832016

COc1c(O)c(O)c(C(=O)c2ccccc2)c(S(=O)(=O)O)c1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
LMNA P02545 4/20 0.46
ALDH1A1 P00352 4/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 3/20 0.43
HSD17B10 Q99714 3/20 0.43
MAPK1 P28482 2/20 0.43
ALOX15 P16050 2/20 0.43
HPGD P15428 4/20 0.39
PDE4A P27815 2/20 0.39
HTT P42858 2/20 0.39
PDE4D Q08499 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP3A4 P08684 2/20 0.39
PGR P06401 1/20 0.39
SLC6A2 P23975 1/20 0.39
HRH1 P35367 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23036909 0.99 MAPT (0.45) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL26110849 0.91 MAPT (0.46) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL489201 0.87 MAPT (0.42) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL26110853 0.85 MAPT (0.46) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL29047180 0.81 MAPT (0.50) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL11776415 0.79 MAPT (0.51) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL28089542 0.78 MAPT (0.50) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL9619784 0.76 LMNA (0.55) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL2048962 0.76 LMNA (0.43) MAPTLMNAALDH1A1KMT2AKDM4E
SCHEMBL4930498 0.75 MAPT (0.42) MAPTLMNAALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10025221-A None JP disclosed
JP-10025220-A None JP disclosed
JP-10025219-A None JP disclosed
EP-0743847-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-05-30 EP disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 EP disclosed
JP-H1025221-A PREPARATION FOR EXTERNAL USE FOR SKIN NOEVIR CO LTD 1998-01-27 JP disclosed
JP-H1025219-A PREPARATION FOR EXTERNAL USE FOR SKIN NOEVIR CO LTD 1998-01-27 JP disclosed
JP-H1025220-A PREPARATION FOR EXTERNAL USE FOR SKIN NOEVIR CO LTD 1998-01-27 JP disclosed
US-5683685-A NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL KAO CORPORATION (JP) 1997-11-04 US disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 WO disclosed
EP-0662314-A1 Method of hair treatment Kao Corporation (JP) 1995-07-12 EP disclosed