Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 2/20 | 0.38 |
| ▸ | PDE4D known ✓ | Q08499 | 2/20 | 0.38 |
| ▸ | PDE4B known ✓ | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C known ✓ | Q08493 | 1/20 | 0.37 |
| ▸ | LY96 known ✓ | Q9Y6Y9 | 1/20 | 0.36 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.35 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832016 | 0.87 | MAPT (0.46) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL23036909 | 0.86 | MAPT (0.45) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL26110849 | 0.81 | MAPT (0.46) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL29047180 | 0.80 | MAPT (0.50) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL11776415 | 0.78 | MAPT (0.51) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL1735933 | 0.78 | LMNA (0.50) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL28089542 | 0.77 | MAPT (0.50) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL26110853 | 0.75 | MAPT (0.46) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| Sulfuric Acid SCHEMBL2878069 | 0.75 | MAPT (0.52) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL170073 | 0.75 | MAPT (0.65) | MAPTKDM4EHSD17B10MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397389-A | Transparent liquid composition and cosmetic containing the same | 株式会社成和化成 | 2022-11-25 | — | — | CN | disclosed |
| EP-3332774-B1 | COMPOSITION FOR SOFT CAPSULE SHELL | FUJI CAPSULE CO LTD (JP) | 2021-09-29 | — | — | EP | disclosed |
| CN-107106507-B | Soft capsule | 富士胶囊有限公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-111032009-A | Skin whitening agent, external skin preparation for whitening skin, and method for whitening skin | 一丸自然美建有限公司 | 2020-04-17 | — | — | CN | disclosed |
| EP-3202395-B1 | SOFT CAPSULE SHELL | FUJI CAPSULE CO LTD (JP) | 2018-12-19 | — | — | EP | disclosed |
| EP-1914264-B1 | SURFACE-TREATED POWDER AND COSMETIC COMPRISING THE SAME | MIYOSHI KASEI INC (JP) | 2018-08-29 | — | — | EP | disclosed |
| US-20180214384-A1 | Composition for Soft Capsule Shell | FUJI CAPSULE CO., LTD. (JP) | 2018-08-02 | — | — | US | disclosed |
| EP-3332774-A1 | COMPOSITION FOR SOFT CAPSULE COATING | Fuji Capsule Co., Ltd. (JP) | 2018-06-13 | — | — | EP | disclosed |
| US-9901547-B2 | Soft capsule shell | FUJI CAPSULE CO., LTD. (JP) | 2018-02-27 | — | — | US | disclosed |
| US-20170292011-A1 | SOFT CAPSULE SHELL | FUJI CAPSULE CO., LTD. (JP) | 2017-10-12 | — | — | US | disclosed |
| EP-1291376-A1 | SILICONE POLYMER, SILICONE COMPOSITION, AND COSMETIC PREPARATION CONTAINING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-03-12 | — | — | EP | disclosed |
| EP-1287807-A1 | COSMETIC PREPARATION | Showa Denko K.K. (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6528068-B1 | An oily material for cosmetic compositions which oily material is an N-long-chain acyl neutral amino acid ester containing a straight-chain or branched-chain, saturated or unsaturated acyl group having from 6 to 22 carbon atoms, where the | AJINOMOTO CO., INC. (JP) | 2003-03-04 | — | — | US | disclosed |
| US-6500415-B2 | OVERCOATED TITANIUM OXIDE | SHOWA DENKO K.K. (JP) | 2002-12-31 | — | — | US | disclosed |
| US-20020115723-A1 | Cysteine derivatives | AJINOMOTO CO., INC. (JP) | 2002-08-22 | — | — | US | disclosed |
| US-20020041853-A1 | Cosmetic composition | SHOWA DENKO K.K. | 2002-04-11 | — | — | US | disclosed |
| WO-2002022098-A2 | SUNSCREEN COSMETIC COMPOSITION | SHOWA DENKO K.K. (JP) | 2002-03-21 | — | — | WO | disclosed |
| EP-1120407-A1 | CYSTEINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-08-01 | — | — | EP | disclosed |
| EP-0992236-A1 | SKIN-LIGHTENING COSMETIC | Sunstar Inc. (JP) | 2000-04-12 | — | — | EP | disclosed |
| EP-0928608-A2 | Cosmetic composition | Ajinomoto Co., Inc. (JP) | 1999-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115723-A1 | Cysteine derivatives | NFE2L2, GCLC, KEAP1 | PDE4A 4320/4885PDE4D 4225/4885PDE4B 4577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.