Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1356361 | 0.99 | LMNA (0.43) | LMNACYP2C19HPGDARCYP1A2 | |
| SCHEMBL26110849 | 0.85 | MAPT (0.46) | LMNACYP2C19HPGDCYP1A2PGR | |
| SCHEMBL29044930 | 0.84 | LMNA (0.43) | LMNACYP2C19HPGDARCYP1A2 | |
| SCHEMBL27643290 | 0.81 | HPGD (0.51) | LMNACYP2C19HPGDARCYP1A2 | |
| SCHEMBL10766603 | 0.76 | HPGD (0.53) | LMNACYP2C19HPGDARCYP1A2 | |
| SCHEMBL7832016 | 0.76 | MAPT (0.46) | LMNACYP2C19HPGDCYP1A2PGR | |
| SCHEMBL23036909 | 0.75 | MAPT (0.45) | LMNACYP2C19HPGDCYP1A2PGR | |
| SCHEMBL8428996 | 0.74 | LMNA (0.51) | LMNACYP2C19HPGDARCYP1A2 | |
| SCHEMBL26110853 | 0.73 | MAPT (0.46) | LMNACYP2C19HPGDCYP1A2PGR | |
| SCHEMBL5181783 | 0.70 | GSTA1 (0.47) | LMNACYP2C19HPGDARCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320531-B1 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2010-09-08 | — | — | EP | claimed |
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2010-02-25 | — | — | US | claimed |
| US-7658769-B2 | Oxidation hair dye composition | HOYU CO., LTD. (JP) | 2010-02-09 | — | — | US | claimed |
| US-20090089940-A1 | Oxidation Hair Dye Composition | HOYU CO., LTD. (JP) | 2009-04-09 | — | — | US | claimed |
| WO-2008083975-A1 | LIGHT-STABILIZED COMPOSITION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008083974-A1 | ACTIVE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008067928-A1 | UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE | ISDIN S.A. (ES) | 2008-06-12 | — | — | WO | claimed |
| JP-5286829-A | — | — | None | — | — | JP | disclosed |
| CN-108366943-B | Hair treatment method | 花王株式会社 | 2022-01-25 | — | — | CN | disclosed |
| EP-3395323-B1 | METHOD FOR TREATING HAIR | KAO CORP (JP) | 2021-09-29 | — | — | EP | disclosed |
| US-20190038532-A1 | METHOD FOR TREATING HAIR | KAO CORPORATION (JP) | 2019-02-07 | — | — | US | disclosed |
| EP-3395323-A1 | HAIR TREATMENT METHOD | Kao Corporation (JP) | 2018-10-31 | — | — | EP | disclosed |
| US-20160120770-A1 | LAYERED DOUBLE HYDROXIDE CAPABLE OF ADSORBING UNSATURATED FATTY ACIDS SELECTIVELY, AND COSMETIC PRODUCED USING SAID LAYERED DOUBLE HYDROXIDE | TAYCA CORPORATION (JP) | 2016-05-05 | — | — | US | disclosed |
| EP-0743847-B1 | HAIR COSMETIC COMPOSITION | KAO CORP (JP) | 2001-05-30 | — | — | EP | disclosed |
| EP-0662314-B1 | Method of hair treatment | KAO CORP (JP) | 1999-11-03 | — | — | EP | disclosed |
| US-5683685-A | NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL | KAO CORPORATION (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0743847-A1 | HAIR COSMETIC COMPOSITION | Kao Corporation (JP) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995020375-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 1995-08-03 | — | — | WO | disclosed |
| EP-0662314-A1 | Method of hair treatment | Kao Corporation (JP) | 1995-07-12 | — | — | EP | disclosed |
| JP-H05286829-A | HAIR TREATING AGENT COMPOSITION | KAO CORP | 1993-11-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | UGT2B17, TACR2, UGT1A1 | LMNA 1819/4885CYP2C19 57/4885HPGD 601/4885 |
| US-20190038532-A1 | METHOD FOR TREATING HAIR | TYR, POLR1C, CA7 | LMNA 2120/4885CYP2C19 1028/4885HPGD 2990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.