Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829714 | 0.89 | SLC10A2 (0.52) | SLC10A2KMT2AKDM4EMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8132935 | 0.89 | SLC10A2 (0.51) | SLC10A2KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL8132448 | 0.85 | EGFR (0.39) | SLC10A2KMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL8133293 | 0.85 | EGFR (0.39) | SLC10A2KMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL8132452 | 0.85 | EGFR (0.39) | SLC10A2KMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL8121479 | 0.84 | SLC10A2 (0.51) | SLC10A2KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7834035 | 0.84 | ALDH1A1 (0.44) | KMT2AKDM4EMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL7818992 | 0.83 | ALDH1A1 (0.43) | SLC10A2KMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL8137994 | 0.83 | SLC10A2 (0.41) | SLC10A2KMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL7835671 | 0.82 | SLC10A2 (0.36) | SLC10A2KMT2AKDM4EMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |
| EP-0634169-B1 | Quinoline or quinazoline derivatives and their use in the manufacture of a medicament for the treatment of osteoporosis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-01-05 | — | — | EP | claimed |