Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832428 | 0.90 | SLC10A2 (0.47) | SLC10A2KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL7832556 | 0.82 | SLC10A2 (0.39) | SLC10A2KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL7834035 | 0.81 | ALDH1A1 (0.44) | KMT2AMEN1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL7835953 | 0.78 | ALDH1A1 (0.43) | SLC10A2KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL14917022 | 0.78 | PDE5A (0.48) | SLC10A2KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL8121664 | 0.77 | FABP3 (0.53) | SLC10A2KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL7830294 | 0.77 | AMY1A (0.40) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7818992 | 0.76 | ALDH1A1 (0.43) | SLC10A2KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL8633281 | 0.76 | ALDH1A1 (0.44) | SLC10A2KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL7834045 | 0.75 | KMT2A (0.40) | SLC10A2KMT2AMEN1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |