Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834045 | 0.80 | KMT2A (0.40) | KDM4EALDH1A1SLC10A2MEN1KMT2A | |
| SCHEMBL7832560 | 0.77 | TDP1 (0.40) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7835960 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1SLC10A2MEN1KMT2A | |
| SCHEMBL8495848 | 0.74 | ALDH1A1 (0.47) | KDM4EALDH1A1SLC10A2MEN1KMT2A | |
| SCHEMBL14917022 | 0.73 | PDE5A (0.48) | KDM4EALDH1A1SLC10A2MEN1KMT2A | |
| SCHEMBL7831686 | 0.72 | FFAR1 (0.40) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8121664 | 0.72 | FABP3 (0.53) | KDM4EALDH1A1SLC10A2MEN1KMT2A | |
| SCHEMBL7831730 | 0.72 | FABP3 (0.44) | KDM4EALDH1A1SLC10A2MEN1KMT2A | |
| SCHEMBL8633281 | 0.71 | ALDH1A1 (0.44) | KDM4EALDH1A1SLC10A2MEN1KMT2A | |
| SCHEMBL3750345 | 0.69 | DHODH (0.54) | KDM4EALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |