Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | FGB | P02675 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835960 | 0.95 | KDM4E (0.41) | KMT2AMEN1HSD17B10MAPK1FGB | |
| SCHEMBL7831686 | 0.92 | FFAR1 (0.40) | KMT2AMEN1HSD17B10MAPK1FGB | |
| SCHEMBL7832565 | 0.80 | KDM4E (0.41) | KMT2AMEN1HSD17B10SLC10A2ALDH1A1 | |
| SCHEMBL8629818 | 0.80 | SLC10A2 (0.55) | KMT2AMEN1HSD17B10MAPK1FGB | |
| SCHEMBL7835666 | 0.78 | ALDH1A1 (0.36) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL7832556 | 0.78 | SLC10A2 (0.39) | KMT2AMEN1HSD17B10SLC10A2ALDH1A1 | |
| SCHEMBL8138452 | 0.78 | ALDH1A1 (0.37) | KMT2AMEN1HSD17B10SLC10A2ALDH1A1 | |
| SCHEMBL8131985 | 0.78 | ALDH1A1 (0.37) | KMT2AMEN1HSD17B10SLC10A2ALDH1A1 | |
| SCHEMBL8131979 | 0.78 | ALDH1A1 (0.37) | KMT2AMEN1HSD17B10SLC10A2ALDH1A1 | |
| SCHEMBL7834035 | 0.76 | ALDH1A1 (0.44) | KMT2AMEN1HSD17B10MAPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |