Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | CBR1 | P16152 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835386 | 0.88 | LOXL2 (0.39) | FFAR1LOXL2LMNAPDE10AALDH1A1 | |
| SCHEMBL7833790 | 0.86 | MAPT (0.38) | FFAR1LOXL2HPGDLMNAMAPT | |
| SCHEMBL7833197 | 0.86 | LOXL2 (0.40) | POLBLOXL2PDE10AMAPTNPC1 | |
| SCHEMBL7829453 | 0.83 | LOXL2 (0.46) | FFAR1LOXL2PDE10AL3MBTL1 | |
| SCHEMBL7831183 | 0.82 | S1PR4 (0.35) | LOXL2SLC6A2HPGDSLC6A3LMNA | |
| SCHEMBL7830320 | 0.81 | S1PR4 (0.36) | LOXL2SLC6A2HPGDSLC6A3LMNA | |
| SCHEMBL7831474 | 0.81 | PDE10A (0.35) | LOXL2SLC6A2HPGDSLC6A3LMNA | |
| SCHEMBL7832013 | 0.80 | KDM5A (0.39) | LMNAPDE10AMAPTHTTL3MBTL1 | |
| SCHEMBL7821057 | 0.79 | LOXL2 (0.37) | LOXL2PDE10A | |
| SCHEMBL7831627 | 0.79 | LOXL2 (0.50) | LOXL2SLC6A3LMNAPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820997-B1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-5985882-A | ANALGESICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0820997-A1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-01-28 | — | — | EP | disclosed |