Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108876 | 0.89 | L3MBTL1 (0.62) | L3MBTL1KDM4ECA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL6569637 | 0.87 | L3MBTL1 (0.60) | L3MBTL1KDM4ECA12CA1CA2 | |
| SCHEMBL1829785 | 0.84 | KDM4E (0.47) | L3MBTL1KDM4EEGLN2FTOKMT2A | |
| SCHEMBL6514167 | 0.84 | TLR7 (0.39) | EGLN2FTOTLR7LMNA | |
| SCHEMBL7833006 | 0.83 | L3MBTL1 (0.55) | L3MBTL1KDM4ECA12CA1CA2 | |
| SCHEMBL3653582 | 0.82 | L3MBTL1 (0.58) | L3MBTL1KDM4EKMT2AMAP2K1 | |
| SCHEMBL312146 | 0.80 | L3MBTL1 (0.60) | L3MBTL1KDM4EKMT2AMAP2K1 | |
| SCHEMBL7842884 | 0.80 | L3MBTL1 (0.44) | L3MBTL1KDM4ECA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL11097642 | 0.79 | L3MBTL1 (0.58) | L3MBTL1KDM4EKMT2AMAP2K1 | |
| SCHEMBL2450038 | 0.77 | L3MBTL1 (0.53) | L3MBTL1KDM4EKMT2AMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162196-A1 | FUSED-RING COMPOUNDS AND USE THEREOF AS DRUGS | JAPAN TOBACCO INC. (JP) | 2001-12-12 | — | — | EP | disclosed |