SCHEMBL108876

SCHEMBL108876

COC(=O)c1ncccc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.62
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
KDM4E B2RXH2 2/20 0.53
EGLN2 Q96KS0 1/20 0.51
FTO Q9C0B1 1/20 0.51
LMNA P02545 1/20 0.50
TSHR P16473 1/20 0.50
TLR7 Q9NYK1 4/20 0.49
MAP2K1 Q02750 1/20 0.46
ALOX15 P16050 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 3/20 0.46
TDP1 Q9NUW8 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
BRD4 O60885 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6569637 0.98 L3MBTL1 (0.60) L3MBTL1CA12CA1CA2CA7
SCHEMBL7833006 0.93 L3MBTL1 (0.55) L3MBTL1CA12CA1CA2CA7
SCHEMBL7833009 0.89 L3MBTL1 (0.51) L3MBTL1CA12CA1CA2CA7
SCHEMBL394073 0.83 L3MBTL1 (0.60) L3MBTL1KDM4ETSHRTLR7MAP2K1
SCHEMBL27832422 0.82 EGLN2 (0.49) L3MBTL1KDM4EEGLN2FTOLMNA
SCHEMBL69177 0.82 L3MBTL1 (0.64) L3MBTL1KDM4ETSHRMAP2K1ALOX15
SCHEMBL3653582 0.81 L3MBTL1 (0.58) L3MBTL1KDM4EMAP2K1ALOX15HTT
SCHEMBL28048185 0.81 TLR7 (0.48) L3MBTL1KDM4EEGLN2FTOLMNA
SCHEMBL27847395 0.81 EGLN2 (0.47) L3MBTL1CA12CA1CA2CA7
SCHEMBL3422060 0.81 EGLN2 (0.47) L3MBTL1KDM4EEGLN2FTOLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 516 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116457345-A Hydroxy pyridine aldoxime skeleton 国家科学研究中心 2023-07-18 CN claimed
CN-105348282-A HIV-1 integrase inhibitor compound as well as preparation method and application thereof UNIV BEIJING TECHNOLOGY 2016-02-24 CN claimed
CN-105294781-A Iridium-europium heterogeneous polynuclear metal complex and its preparation method and use UNIV XIANGTAN 2016-02-03 CN claimed
US-20260103451-A1 PROCESS FOR PREPARING PYRIMIDINYL BIPYRIDINE COMPOUND AND INTERMEDIATE THEREFOR BEYONDBIO INC (KR) 2026-04-16 US disclosed
US-12527790-B2 Checkpoint kinase 1 (CHK1) inhibitors and uses thereof BOUNDLESS BIO, INC. (US) 2026-01-20 US disclosed
US-20260008787-A1 FUSED RING KRAS INHIBITORS FOR TREATING DISEASE BLOSSOMHILL THERAPEUTICS INC (US) 2026-01-08 US disclosed
US-12459929-B2 GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use CARMOT THERAPEUTICS INC. (US) 2025-11-04 US disclosed
EP-2958562-B1 ANTIDIABETIC BICYCLIC COMPOUNDS MERCK SHARP & DOHME LLC (US) 2025-09-10 EP disclosed
US-12371418-B2 Process for preparing pyrimidinyl bipyridine compound and intermediate therefor BEYONDBIO INC. (KR) 2025-07-29 US disclosed
EP-4563199-A2 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE Carmot Therapeutics, Inc. (US) 2025-06-04 EP disclosed
US-20250154137-A1 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE CARMOT THERAPEUTICS, INC. 2025-05-15 US disclosed
EP-0249707-A1 Picolinic acid derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-12-23 EP disclosed
EP-0045281-B1 TRIAZOLINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION CIBA-GEIGY AG (CH) 1985-05-08 EP disclosed
US-4426526-A HISTAMINE ANTAGONISTS, ANTIINFLAMMATORY, ANTISECRETORY SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1984-01-17 US disclosed
US-4406905-A COMPLEXING, ANTIBIOTICS CIBA-GEIGY CORPORATION (US) 1983-09-27 US disclosed
EP-0045281-A1 Triazoline derivatives and processes for their preparation CIBA-GEIGY AG (CH) 1982-02-03 EP disclosed
US-4264608-A HISTAMINE ANTAGONISTS SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1981-04-28 US disclosed
US-4215126-A HISTAMINE H2 BLOCKING SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1980-07-29 US disclosed
US-4156727-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-05-29 US disclosed
US-4154838-A ANTIHISTAMINE SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154137-A1 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE GLP1R, GCGR, GIPR L3MBTL1 4709/4885CA12 4411/4885CA1 4627/4885
US-12459929-B2 GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use GLP1R, GCGR, GIPR L3MBTL1 4709/4885CA12 4411/4885CA1 4627/4885
US-20260103451-A1 PROCESS FOR PREPARING PYRIMIDINYL BIPYRIDINE COMPOUND AND INTERMEDIATE THEREFOR CCND1, CCND2, CDK2 L3MBTL1 2295/4885CA12 4541/4885CA1 1741/4885
US-12527790-B2 Checkpoint kinase 1 (CHK1) inhibitors and uses thereof CHEK1, RAD1, CHEK2 L3MBTL1 828/4885CA12 2793/4885CA1 2028/4885
US-20260008787-A1 FUSED RING KRAS INHIBITORS FOR TREATING DISEASE KRAS, NRAS, HRAS L3MBTL1 2943/4885CA12 2545/4885CA1 3143/4885
US-12371418-B2 Process for preparing pyrimidinyl bipyridine compound and intermediate therefor WEE1, GGPS1, WEE2 L3MBTL1 4602/4885CA12 4818/4885CA1 4772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.