Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535696 | 0.95 | L3MBTL1 (0.48) | L3MBTL1TLR7ACLYRORCKDM4E | |
| SCHEMBL7839731 | 0.82 | SLC6A4 (0.43) | L3MBTL1TLR7ACLYKDM4ETDP1 | |
| SCHEMBL3866652 | 0.81 | BRD4 (0.49) | KDM4ERAB9AALDH1A1 | |
| SCHEMBL108876 | 0.81 | L3MBTL1 (0.62) | L3MBTL1TLR7EGLN2FTOKDM4E | |
| SCHEMBL7833009 | 0.80 | L3MBTL1 (0.51) | L3MBTL1TLR7EGLN2FTOKDM4E | |
| SCHEMBL756477 | 0.80 | L3MBTL1 (0.46) | L3MBTL1TLR7ACLYRORCKDM4E | |
| Hydrochloric Acid SCHEMBL6569637 | 0.79 | L3MBTL1 (0.60) | L3MBTL1TLR7EGLN2FTOKDM4E | |
| SCHEMBL7833006 | 0.78 | L3MBTL1 (0.55) | L3MBTL1TLR7EGLN2FTOKDM4E | |
| SCHEMBL31471005 | 0.76 | L3MBTL1 (0.53) | L3MBTL1TLR7NFE2L2 | |
| SCHEMBL3653582 | 0.75 | L3MBTL1 (0.58) | L3MBTL1KDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162196-A1 | FUSED-RING COMPOUNDS AND USE THEREOF AS DRUGS | JAPAN TOBACCO INC. (JP) | 2001-12-12 | — | — | EP | disclosed |