Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833350 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CYP2C9POLBCYP2C19LPAR2 | |
| SCHEMBL9364381 | 0.84 | LPAR2 (0.63) | ALDH1A1CYP2C9POLBCYP2C19LPAR2 | |
| SCHEMBL7826073 | 0.84 | ALDH1A1 (0.65) | ALDH1A1CYP2C9POLBCYP2C19LPAR2 | |
| SCHEMBL7826069 | 0.84 | ALDH1A1 (0.65) | ALDH1A1CYP2C9POLBCYP2C19LPAR2 | |
| SCHEMBL9364375 | 0.84 | LPAR2 (0.63) | ALDH1A1CYP2C9POLBCYP2C19LPAR2 | |
| SCHEMBL7814579 | 0.83 | MMP1 (0.71) | ALDH1A1CYP2C9LPAR2LPAR3MAPT | |
| SCHEMBL30764101 | 0.83 | MMP1 (0.71) | ALDH1A1CYP2C9LPAR2LPAR3MAPT | |
| SCHEMBL7814581 | 0.83 | MMP1 (0.71) | ALDH1A1CYP2C9LPAR2LPAR3MAPT | |
| SCHEMBL10493789 | 0.83 | KDM4E (0.63) | ALDH1A1CYP2C9POLBCYP2C19LPAR2 | |
| SCHEMBL10493785 | 0.83 | KDM4E (0.63) | ALDH1A1CYP2C9POLBCYP2C19LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |