Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.63 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364375 | 1.00 | LPAR2 (0.63) | LPAR2LPAR3KDM4EMAPTPKM | |
| SCHEMBL7814579 | 0.86 | MMP1 (0.71) | LPAR2LPAR3KDM4EMAPTPKM | |
| SCHEMBL7814581 | 0.86 | MMP1 (0.71) | LPAR2LPAR3KDM4EMAPTPKM | |
| SCHEMBL30764101 | 0.86 | MMP1 (0.71) | LPAR2LPAR3KDM4EMAPTPKM | |
| SCHEMBL10493785 | 0.85 | KDM4E (0.63) | LPAR2LPAR3KDM4EMAPTPKM | |
| SCHEMBL10493789 | 0.85 | KDM4E (0.63) | LPAR2LPAR3KDM4EMAPTPKM | |
| SCHEMBL7833350 | 0.84 | ALDH1A1 (0.62) | LPAR2LPAR3KDM4EMAPTPKM | |
| SCHEMBL7833348 | 0.84 | ALDH1A1 (0.62) | LPAR2LPAR3KDM4EMAPTPKM | |
| SCHEMBL13576581 | 0.83 | MMP1 (0.80) | MAPTMEN1KMT2ALMNAEGFR | |
| SCHEMBL7825352 | 0.83 | LPAR2 (0.48) | LPAR2LPAR3KDM4EMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403240-B1 | Preparation process of N-substituted maleimides | MITSUI TOATSU CHEMICALS (JP) | 1994-08-24 | — | — | EP | claimed |
| EP-0372922-B1 | Preparation process of N-substituted maleimides | MITSUI TOATSU CHEMICALS (JP) | 1994-03-09 | — | — | EP | claimed |
| US-5175309-A | Forming an imide by heat catalytic dehydration | MITSUI TOATSU CHEMICALS INC. (JP) | 1992-12-29 | — | — | US | claimed |
| US-5068357-A | Heat dehydration of an N-substituted maleamic acid with a solvent, distillation after imidation, in the presence of a tin catalyst | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-11-26 | — | — | US | claimed |
| EP-0403240-A1 | Preparation process of N-substituted maleimides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-12-19 | — | — | EP | claimed |
| EP-0372922-A2 | Preparation process of N-substituted maleimides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-06-13 | — | — | EP | claimed |
| EP-0403240-B1 | Preparation process of N-substituted maleimides | MITSUI TOATSU CHEMICALS (JP) | 1994-08-24 | — | — | EP | disclosed |
| EP-0372922-B1 | Preparation process of N-substituted maleimides | MITSUI TOATSU CHEMICALS (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5175309-A | Forming an imide by heat catalytic dehydration | MITSUI TOATSU CHEMICALS INC. (JP) | 1992-12-29 | — | — | US | disclosed |
| US-5068357-A | Heat dehydration of an N-substituted maleamic acid with a solvent, distillation after imidation, in the presence of a tin catalyst | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0403240-A1 | Preparation process of N-substituted maleimides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-12-19 | — | — | EP | disclosed |
| EP-0372922-A2 | Preparation process of N-substituted maleimides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-06-13 | — | — | EP | disclosed |