Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833366 | 0.93 | MAPT (0.42) | AMY1AENPP1CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL7833295 | 0.90 | SLC10A2 (0.45) | AMY1AENPP1MAPTSMN1; SMN2FPR2 | |
| SCHEMBL7831401 | 0.89 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2KMT2AHTTTP53 | |
| SCHEMBL7831847 | 0.84 | SLC10A2 (0.45) | AMY1AENPP1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7821021 | 0.83 | MAPK1 (0.53) | CYP1A2MAPTSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7834113 | 0.81 | SMN1; SMN2 (0.52) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL7829964 | 0.80 | ALDH1A1 (0.45) | MAPTSMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL7829702 | 0.79 | SMN1; SMN2 (0.51) | MAPTSMN1; SMN2KMT2ATUBB4ATUBB | |
| SCHEMBL7836104 | 0.77 | FABP3 (0.44) | CYP2C9CYP2C19CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL14917022 | 0.77 | PDE5A (0.48) | MAPTSMN1; SMN2KMT2ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |