Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843015 | 0.79 | LMNA (0.46) | LMNATSPOMMP1MMP2MMP3 | |
| SCHEMBL9676806 | 0.77 | LMNA (0.44) | LMNATSPOMMP1MMP2MMP3 | |
| SCHEMBL968674 | 0.76 | — | — | |
| SCHEMBL5619620 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4E | |
| SCHEMBL8426445 | 0.73 | LMNA (0.50) | LMNATSPOMMP1MMP2MMP3 | |
| SCHEMBL206810 | 0.73 | LMNA (0.50) | LMNATSPOMMP1MMP2MMP3 | |
| SCHEMBL4943847 | 0.71 | LMNA (0.48) | LMNATSPOMMP1MMP2MMP3 | |
| SCHEMBL1405183 | 0.71 | LMNA (0.48) | LMNATSPOMMP1MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL5796983 | 0.70 | LMNA (0.46) | LMNATSPOMMP1MMP2MMP3 | |
| SCHEMBL400638 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105376-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010975-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2000-03-02 | — | — | WO | disclosed |