Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833290 | 0.90 | SLC10A2 (0.46) | ALDH1A1POLBGLAMEN1KMT2A | |
| SCHEMBL7831401 | 0.81 | SMN1; SMN2 (0.54) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7821021 | 0.80 | MAPK1 (0.53) | ALDH1A1TSHRMAPK1MAPTHPGD | |
| SCHEMBL7836104 | 0.79 | FABP3 (0.44) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL14917022 | 0.79 | PDE5A (0.48) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7821085 | 0.79 | MAPT (0.44) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL7832560 | 0.78 | TDP1 (0.40) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL8121664 | 0.78 | FABP3 (0.53) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL8633281 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7834035 | 0.76 | ALDH1A1 (0.44) | ALDH1A1POLBMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |