Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 17/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833907 | 1.00 | AAK1 (0.36) | AAK1ACACBACACAABL1BCR | |
| SCHEMBL7231706 | 0.93 | AAK1 (0.36) | AAK1ACACBACACAABL1BCR | |
| SCHEMBL7238123 | 0.83 | ABL1 (0.35) | AAK1ACACBACACAABL1BCR | |
| SCHEMBL7841629 | 0.79 | ACACB (0.35) | AAK1ACACBACACA | |
| SCHEMBL7833912 | 0.79 | CNR1 (0.34) | AAK1ACACBACACAABL1BCR | |
| SCHEMBL7238064 | 0.76 | AAK1 (0.41) | AAK1ACACBACACA | |
| SCHEMBL7231006 | 0.73 | AAK1 (0.45) | AAK1ABL1BCR | |
| SCHEMBL7229865 | 0.71 | CNR1 (0.43) | AAK1ACACBACACAABL1BCR | |
| SCHEMBL7844289 | 0.69 | ACACB (0.34) | AAK1ACACBACACAABL1BCR | |
| SCHEMBL7228914 | 0.67 | SIGMAR1 (0.41) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157022-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000049015-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |