Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.33 |
| ▸ | ABL1 | P00519 | 4/20 | 0.33 |
| ▸ | BCR | P11274 | 4/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841629 | 0.88 | ACACB (0.35) | CNR1AAK1ACACBACACA | |
| SCHEMBL7833907 | 0.79 | AAK1 (0.36) | AAK1ABL1BCRACACBACACA | |
| SCHEMBL7833910 | 0.79 | AAK1 (0.36) | AAK1ABL1BCRACACBACACA | |
| SCHEMBL7844289 | 0.78 | ACACB (0.34) | AAK1ABL1BCRACACBACACA | |
| SCHEMBL7231706 | 0.76 | AAK1 (0.36) | CNR1AAK1ABL1BCRACACB | |
| SCHEMBL7843956 | 0.71 | AAK1 (0.39) | CNR1AAK1ACACBACACALMNA | |
| SCHEMBL7846551 | 0.67 | CNR1 (0.52) | CNR1ACACBACACALMNANPSR1 | |
| SCHEMBL7238123 | 0.67 | ABL1 (0.35) | AAK1ABL1BCRACACBACACA | |
| SCHEMBL7238992 | 0.65 | CYP2A6 (0.38) | CNR1ABL1BCRLMNANPSR1 | |
| SCHEMBL7238064 | 0.62 | AAK1 (0.41) | CNR1AAK1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157022-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000049015-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |