Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193039 | 0.92 | PTGS2 (0.48) | PTGS2PTGS1ALDH1A1HTTLMNA | |
| SCHEMBL4176052 | 0.80 | HTT (0.50) | PTGS2PTGS1ALDH1A1HTTLMNA | |
| SCHEMBL4185514 | 0.78 | PTGS2 (0.54) | PTGS2PTGS1ALDH1A1HTTLMNA | |
| SCHEMBL4182856 | 0.76 | PTGS2 (0.54) | PTGS2PTGS1ALDH1A1HTTLMNA | |
| SCHEMBL4187497 | 0.75 | ALDH1A1 (0.44) | PTGS2PTGS1ALDH1A1HTTLMNA | |
| SCHEMBL4384062 | 0.72 | PTGS2 (0.60) | PTGS2PTGS1ALDH1A1HTTHSD17B10 | |
| SCHEMBL4804773 | 0.72 | PTGS2 (0.61) | PTGS2PTGS1ALDH1A1HTTHSD17B10 | |
| SCHEMBL10255330 | 0.72 | NPBWR1 (0.67) | PTGS2PTGS1ALDH1A1HTTHSD17B10 | |
| SCHEMBL4194402 | 0.70 | NPBWR1 (0.47) | ALDH1A1PPARGNCOA2NCOA1NPSR1 | |
| SCHEMBL4186872 | 0.70 | ALDH1A1 (0.39) | ALDH1A1LMNAPPARGNCOA2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124804-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024719-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2000-05-04 | — | — | WO | disclosed |