Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690937 | 0.88 | GPR84 (0.32) | ALDH1A1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8691126 | 0.87 | GPR84 (0.32) | HTR2AHTR2CHTR2BFFAR1GPR84 | |
| SCHEMBL8692253 | 0.75 | MPO (0.31) | GPR84 | |
| SCHEMBL8690737 | 0.72 | HTR2C (0.40) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28673229 | 0.66 | GPR84 (0.60) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL2936407 | 0.61 | — | — | |
| SCHEMBL2452615 | 0.61 | KMT2A (0.34) | MEN1KMT2AALDH1A1HSD17B10MAPT | |
| SCHEMBL3747922 | 0.60 | — | — | |
| SCHEMBL3374528 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL27640049 | 0.59 | MEN1 (0.49) | MEN1KMT2AALDH1A1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861248-B1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PROD (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0861248-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5750724-A | SEROTONIN 5-HT REUPTAKE INHIBITORS; ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997017343-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |