Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.40 |
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | HTR1D | P28221 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817689 | 0.81 | HTR2C (0.39) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL7824590 | 0.73 | MPO (0.41) | HTR2CHTR2ATSHRSLC6A4ALDH1A1 | |
| SCHEMBL7834306 | 0.72 | HDAC3 (0.33) | HTR2CHTR2AHTR2BCYP2D6CYP1A2 | |
| SCHEMBL7818121 | 0.71 | MPO (0.45) | HTR1ASLC6A4MPO | |
| SCHEMBL8690899 | 0.70 | MPO (0.31) | SLC6A4MPO | |
| SCHEMBL7825966 | 0.70 | MPO (0.42) | HTR1ASLC6A4MPO | |
| SCHEMBL8690937 | 0.69 | GPR84 (0.32) | HTR2CHTR2AHTR2BCYP2D6CYP1A2 | |
| SCHEMBL8692253 | 0.69 | MPO (0.31) | MPO | |
| SCHEMBL7817703 | 0.69 | HTR2A (0.43) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL7824434 | 0.68 | HTR2A (0.44) | HTR2CHTR1AHTR2AHTR2BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750724-A | SEROTONIN 5-HT REUPTAKE INHIBITORS; ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-12 | — | — | US | claimed |